Music Restores Propriospinal Excitation During Stroke Locomotion

Music-based therapy for rehabilitation induces neuromodulation at the brain level and improves the functional recovery.In line with this, musical rhythmicity improves post-stroke gait.Moreover, an external distractor also helps stroke patients to improve locomotion.We raised the question whether music with irregular tempo (arrhythmic music), and it

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The dual role of CXCL9/SPP1 polarized tumor-associated macrophages in modulating anti-tumor immunity in hepatocellular carcinoma

IntroductionThe main challenge for cancer therapy lies in immuno-suppressive tumor micro-environment.Reprogramming tumor-associated macrophages (TAMs) into an anti-tumor phenotype is a promising strategy.MethodsA comprehensive analysis by combing multi-regional single-cell, bulk and spatial transcriptome profiling with radiomics characterization wa

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